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Pregabalin/Effexor/Zoloft. - November 26th 2012, 01:35 PM

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Hello hello hello fellow THers. I'm like some advice.

I'm hoping to change ADs 'cause Zoloft is smashing up my short-term memory and the GP is concerned that I'll end up like the lass from 50 first dates if I keep at it, so I'm going to maybe be taking effexor/venlafaxine instead.
But first, I'm coming off the Pregabalin/Lyrica because it's lame and I don't even remember what it's for...but I think it's to help with anxiety in my case. Anyway, the internet is pretty useless when it comes to pregabalin 'cause it's used for MS/FM and chronic pain problems, so most people report being in pain when they stopped taking it. Usually I know what to expect with withdrawal from ADs but these aren't an AD and I wondered if anyone else has come off these?

I'm a real super sensitive softie to medication so I always get well tripped up side effects and withdrawal...I'm just kinda hoping this won't be too excruciating or agonisingly triggering like the others. I think last time I quit a drug I ended up sobbing down the phone to the crisis team every day for a week :/

Also, Mr GP said the problem with effexor is the withdrawal will be badbadbad with a capital B which is why he never prescribes it anymore. Now I know it's similar to duloxetine which I've taken before, so I'm guessing that when I do decide to come off it...the side effects will be the same if not worse, so again....anyone got experience with these magic pills?

Ta for the advice in advance. [Heh, advice in advance] Sorry for the looooong post.
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Re: Pregabalin/Effexor/Zoloft. - November 26th 2012, 09:00 PM

I have taken venlafaxine before.. I don't think I would ever take it again though because the withdrawls are horrible. If I didn't take it for a day I would feel it. When I stopped taking it suddenly it gave me brain zaps, I felt twice as bad and just totally out of it. I just strongly advise never to stop it suddenly because of the withdrawls.

I hope it works for you

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Re: Pregabalin/Effexor/Zoloft. - December 3rd 2012, 10:21 AM

I've been on effexor. It can cause heart damage in conjunction with other medications I think (and I think that is what happened to me).

And yes, the withdrawal is somewhat nasty. It has a very high withdrawal rate, much higher than most meds. For me, that meant lying around incapacitated while biting/clawing myself for a couple days. I don't recommend it.

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Re: Pregabalin/Effexor/Zoloft. - December 4th 2012, 03:58 AM

I was on Effexor when I was in College. I found it actually made me more depressed and anxiouus than I already was and in the end things ended badly (it made me depressed enough to make an attempt on my life).
as far as side effects go, I don't think I really had any. Although since I've come off it I've had "brain zaps" and seeing as its been like 3 years I guess they're not going away. I also believe that my memory has been impaired somehow since taking it but while doctors will agree with me that its possible none of them will really look into it for me so oh well.

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Re: Pregabalin/Effexor/Zoloft. - December 4th 2012, 06:30 AM

Another for saying effexor is a horrible drug! I was on that transitioning between meds a few years ago, if I took it 2 hours late I would get headaches and sickness, it was horrible! Are there any other drugs you can try? If its your GP prescribing he should refer you to a psychiatrist as these drugs can be dangerous and you need to be under the guidance of a specialist..

My spelling is terrible, so I'm sorry for any spelling mistakes in my posts
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Re: Pregabalin/Effexor/Zoloft. - December 4th 2012, 06:51 AM

Zoloft screwed me over too! Lol.

Have you tried Remeron? It can make you hungry and sometimes tired (zombies need sugar!), but I think it's overlooked in my opinion. And it works faster than traditional SSRIs. It's pretty effective for me.

I assume you tried Prozac?

Also, maybe you could consider e-cigarettes or nicotine patches. I don't smoke, lol, but it has helped some family members of mine.
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