Well in my couse it's pretty much legitimately impossible to do all of the readings. (500pgs+ x4 classes, plus assignments and things) So I've found I tend to go to class, and if there's a concept i'm fuzzy on it don't understand then do the readings assigned after the class
Probably not the ideal way to do things but it tends to work. You just have to make sure that if there's even a tiny thing you're not sure on you look it up. Also if it looks like a certain week is going to be a tricky week, do it in advanced then.
Another tip - I'm not sure how uni-ness works for you, but we often have different readings assigned for lectures and tutorials. Tutorial readings are the most important, but lecture ones can be left by the wayside.
Also, if you have assignment topics and things, make sure you read the weeks readings for the one it corresponds to.