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SexySquirrel Offline
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Question pancreatitis and prophyria - February 22nd 2009, 12:25 AM

well, during the time i was in the ER earlier this week, i found out that i have pancreatitis. I don't really know much about it, i've tried looking it up online but i keep getting confused, does anyone know anything about it? i would appreciate it if you could try to explain to me what it is. all that i know is that it is VERY painful. the doctors dont know what's causing it, so they cant treat it.
i am also getting tested for prophyria, but i also dont understand what that is, if anyone can help expalain, please do.
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Re: pancreatitis and prophyria - February 22nd 2009, 12:38 AM

according to wikipedia, porphyria is "a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway." and the "heme biosynthetic pathway" basically means the process your body uses to create heme.

further down the article it says "heme [is] an essential constituent of hemoglobin, myoglobin, catalase, peroxidase, respiratory and P450 liver cytochromes." and these are all pretty important proteins. like hemoglobin carries oxygen and carbon dioxide around in your blood. and peroxidase helps break down waste products. so i imagine if you're having trouble producing heme it could screw a bunch of things up

but then if you read further it says the main problem isn't not having enough heme, it's that when you can't make heme from its ingredients (the porphyrins) the ingredients build up in your body, and that poisons your body

so that's how it works.
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Re: pancreatitis and prophyria - February 22nd 2009, 12:41 AM

Porphyrias are a group of genetic disorders caused by problems with how your body makes a substance called heme. Heme is found throughout the body, especially in your blood and bone marrow, where it carries oxygen.
Porphyrias affect the skin or the nervous system. People with the skin type develop blisters, itching, and swelling of their skin when it is exposed to sunlight. The nervous system type is called acute porphyria. Symptoms include pain in the chest or abdomen, vomiting, and diarrhea or constipation. During an attack, symptoms can include muscle numbness, tingling, paralysis, cramping, and personality or mental changes. Certain triggers can cause an attack, including some medicines, smoking, drinking alcohol, infections, stress and sun exposure. Attacks develop over hours or days. They can last for days or weeks.
Porphyria can be hard to diagnose. It requires blood, urine and stool tests. Each type has a different treatment. It usually involves medicine, treatment with heme or drawing blood.
National Institute of Diabetes and Digestive and Kidney Diseases
For more information about Porphyria you can go to : http://www.nlm.nih.gov/medlineplus/porphyria.html

The pancreas is a large gland located behind the stomach and next to the duodenum (the first section of the small intestine). The pancreas has two primary functions:

To secrete powerful digestive enzymes into the small intestine to aid the digestion of carbohydrates, proteins, and fat.
To release the hormones insulin and glucagon into the bloodstream. These hormones are involved in blood glucosemetabolism, regulating how the body stores and uses food for energy.
Pancreatitis is a disease in which the pancreas becomes inflamed. Pancreatic damage occurs when the digestive enzymes are activated before they are secreted into the duodenum and begin attacking the pancreas.

There are two forms of pancreatitis: acute and chronic.
for more information on pancreatitis go to : http://www.webmd.com/digestive-disor...s-pancreatitis

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Re: pancreatitis and prophyria - February 22nd 2009, 12:46 AM

Prophyria is a disease that affects your nervous system.

You can get really bad stomach pain, vomiting, constipation/diarrhoea, bad headaches, seizures and sometimes stuff that affects your mental health. Its been known to cause depression, anxiety. The pain that comes with prophyria is known to be really bad. In general, testing involves sending samples of blood, stool and urine to a reference laboratory for them to check out.

There are ways to limit the attacks severeness. ones called hematin. Eating a rich carbohydrate diet has also be known to limit the severeness of the attacks.

Taking a hot/cold bath might help take some of the pain away?

Pancreatitis is where your pancreas gets inflammed. Mild cases can be treated by IV fluids but more severe cases ICU or surgery.

Hope this helps?

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Re: pancreatitis and prophyria - February 22nd 2009, 02:06 AM

If what others have said still confuses you calling your doctors office and asking them to further explain what they are can be a bit more helpful.

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